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Computer vision syndrome

Computer vision syndrome (CVS) is a temporary condition resulting from focusing the eyes on a computer display for protracted, uninterrupted periods of time. Some symptoms of CVS include headaches, blurred vision, neck pain, fatigue, eye strain, dry, irritated eyes, and difficulty refocusing the eyes. These symptoms can be further aggravated by improper lighting conditions (ie. bright overhead lighting or glare) or air moving past the eyes.

Brushfield spots in Down's syndrome

Brushfield spots are small white or grayish/brown spots on the periphery of the iris in the human eye due to aggregation of connective tissue, a normal iris element. These spots are normal in children but are also a feature of the chromosomal disorder Down syndrome. They occur in 35-78% of newborn infants with Down syndrome.They are much more likely to occur in Down syndrome children of the Caucasian race than children of Asian heritage.Brushfield spots are named after the physician, Thomas Brushfield, who first described them in his 1924 M.D. thesis.They are focal areas of stromal hyperplasia, surrounded by relative hypoplasia and are more common in patients with lightly pigmented irises.

Simian crease-single palmar flexion crease

TS A simian crease is a single palmar crease as compared to two creases in a normal palm. Simian crease occurs in about 1 out of 30 normal people, but is also frequently associated with other conditions such as * Down syndrome * Aarskog syndrome * Fetal alcohol syndrome * cri du chat syndrome (chromosome 5) * Noonan syndrome (chromosome 12) * Patau syndrome (chromosome 13) * Edward's syndrome (chromosome