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Showing posts from August, 2009

Computer vision syndrome

Computer vision syndrome (CVS) is a temporary condition resulting from focusing the eyes on a computer display for protracted, uninterrupted periods of time. Some symptoms of CVS include headaches, blurred vision, neck pain, fatigue, eye strain, dry, irritated eyes, and difficulty refocusing the eyes. These symptoms can be further aggravated by improper lighting conditions (ie. bright overhead lighting or glare) or air moving past the eyes.

Cafe coronary

This is a condition in which a healthy but grossly intoxicated person, who begins a meal, suddenly turns blue, coughs violently, then collapses and dies without much fuss. Death appears to due to sudden heart attack. Treatment : A blow on the back or on the sternum may cause coughing and expel the foreign body. if this is not successful, the foreign body must be removed from the hypopharynx with the middle and index fingers or with forceps.

Difference between splenomegaly and hypersplenism

Splenomegaly It is just an enlargement of spleen. It may be * Mild * Moderate or * Severe Hypersplenism This is a pancytopenia occurring in patients with an enlarged spleen. It is due to large numbers of cells being pooled and destroyed in the spleen's reticuloendothelial system, and haemodilution because of an increased plasma volume.

Kawasaki disease

Kawasaki disease may be rare, but it's now the commonest cause of acquired heart disease in children under 5. It's an acute, self limiting, multiorgan vasculitis of unknown cause. The problem is the vasculitis tends to affect coronary arteries and can cause sudden death if untreated. Immunoglobulins and aspirin reduce cardiac complications significantly.Diagnosis is essentially clinical-fever for five days and at least 4 of the following: * Red eyes (bilateral conjunctivitis, no pus) * Sore red mouth, * red cracked lips, and * classically a "strawberry" tongue with protuberant papillae * Polymorphous maculopapular skin rash * Cervical lymphadenopathy, usually unilateral and >1.5 cm in diameter * Erythema and oedema of the hands and feet (with desquamation of the skin in the later stage of the illness). Source: Heart 2009;95:787-792

Brushfield spots in Down's syndrome

Brushfield spots are small white or grayish/brown spots on the periphery of the iris in the human eye due to aggregation of connective tissue, a normal iris element. These spots are normal in children but are also a feature of the chromosomal disorder Down syndrome. They occur in 35-78% of newborn infants with Down syndrome.They are much more likely to occur in Down syndrome children of the Caucasian race than children of Asian heritage.Brushfield spots are named after the physician, Thomas Brushfield, who first described them in his 1924 M.D. thesis.They are focal areas of stromal hyperplasia, surrounded by relative hypoplasia and are more common in patients with lightly pigmented irises.

Simian crease-single palmar flexion crease

TS A simian crease is a single palmar crease as compared to two creases in a normal palm. Simian crease occurs in about 1 out of 30 normal people, but is also frequently associated with other conditions such as * Down syndrome * Aarskog syndrome * Fetal alcohol syndrome * cri du chat syndrome (chromosome 5) * Noonan syndrome (chromosome 12) * Patau syndrome (chromosome 13) * Edward's syndrome (chromosome

Longest ever English word

According to the oxford dictionary the word is Pneumonouthramicros cpopicsilicovolc anocon . This 45 letter word was coined the longest ever to appear in the dictionary. It means a lung disease caused by the inhalation of volcanic ash causing inflammation in the lungs.

Diabetes treatment newer trends

Source: BMJ 2009;338:b1668 New NICE guidelines in the UK on newer drugs for use in diabetes are summarised in the BMJ. Some key points are: Add sitagliptin (a DPP-4 inhibitor) as second line treatment with metformin instead of a sulphonylurea when blood glucose control is inadequate if sulphonylureas are contraindicated or if the patient is at risk of hypoglycaemia Add sitagliptin or a thiazolidinedione (pioglitazone or rosiglitazone) as a third line treatment if metformin and a sulphonylurea are not adequately controlling blood glucose and insulin is unsuitable Don't use thiazolidinediones in patients with heart failure or at high risk of fracture Add pioglitazone to insulin therapy if a thiazolidinedione has lowered blood glucose in the past or if high dose insulin is not adequately controlling blood glucose.

Tamiflu altenative

Tamiflu is a drug that slows down spread of non resistant strains of h1n1 virus between cells of body Its adult dose is 75mg twice daily for 5 days taken within 2days of appearance of symptoms But resistance is the major problem of concern In the presence of resistance second line drugs like Relenza(zenamivir) can be taken