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Simian crease-single palmar flexion crease

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TS


A simian crease is a single palmar crease as compared to two creases in a normal palm. Simian crease occurs in about 1 out of 30 normal people, but is also frequently associated with other conditions such as

* Down syndrome
* Aarskog syndrome
* Fetal alcohol syndrome
* cri du chat syndrome (chromosome 5)
* Noonan syndrome (chromosome 12)
* Patau syndrome (chromosome 13)
* Edward's syndrome (chromosome
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