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Difference between splenomegaly and hypersplenism

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Splenomegaly
It is just an enlargement of spleen. It may be

* Mild
* Moderate or
* Severe

Hypersplenism
This is a pancytopenia occurring in patients with an enlarged spleen. It is due to large numbers of cells being pooled and destroyed in the spleen's reticuloendothelial system, and haemodilution because of an increased plasma volume.
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