ScoopMed

Neurotransmitters  Chemical transmitters involved in transmission of impulse from one nerve to another. In other words, it is involved in the conduction of impulse. Eg : GABA, Glycine Neuromodulators  Chemicals which by itself does not have any effect or a minimal effect but modulates the activity of other neurotransmitters or receptors. The neuromodulators can either amplify or dampen the effect of neurotransmitters. Many neurotransmitters also behave as neuromodulators at specific sites. Eg : Substance P (both neurotransmitter and neuromodulator)

The anti malarial drugs is one such thing where recalling the names itself is like repeating a tongue twister. But here is a story which helps to retain the important points about the mechanism, adverse effects, uses of these drugs. Antimalarials: The Harem Once upon a time in a parallel Universe, there was a swampy kingdom ruled by King Medico. So, the story goes that once the kingdom was attacked by an epidemic of Malaria (Attack of the Plasmodia). The King (who is you in this story) decided to send his Queens out to destroy Malaria (much like in Chess: the Queen goes out to destroy, the King sits at home and watches ESPN!) He had 10 queens (including one eunuch), a mafia couple, a cyclist-warrior, a new warrior, and a CIA agent. Chloe-Queen (Chloroquine). Right, so…Chloe the Queen was a pretty effective warrior; she fought fast and long. The parasites had occupied the Temples of the Red Corpuscles and were trying to degrade the sacred substance Heme, but she complexed with Heme an...